Stem Cell Nutrition -- Video and Articles

Watch the Stem Cell Nutrition Product Video: Click Here.

Stem Cell Health is simple and natural. Embrionic Stem Cells are Controversial Conversation. Consequently Stem Cells are hot political news. We are interested only in what everyone agrees about -- no bull here.

Thursday, February 28, 2008

StemEnhance™ Product Description

StemEnhance - stem cell enhancer

StemEnhance™ is a blend of two compounds extracted from the cyanophyta Aphanizomenon flos-aquae (AFA). These compounds are extracted using a proprietary process that utilizes no chemicals or harsh agents.

One extract, which contains an L-selectin
, supports the release of stem cells (CD34+
cells) from the bone marrow. The other extract, a polysaccharide-rich
fraction named Migratose™
, may support
the migration of stem cells out of the blood into tissues.

Effectiveness of StemEnhance™ was demonstrated
in a triple-blind study. Volunteers rested for one hour before
establishing baseline levels. After the first blood samples, volunteers
were given StemEnhance or placebo. Thereafter, blood samples were taken
at 30, 60 and 120 minutes after taking the consumables. The number of
circulating stem cells was quantified by analyzing the blood samples
using Fluorescence-Activated Cell Sorting (FACS). Consumption
of StemEnhance™ triggered a significant 25-30% increase in
the number of circulating stem cells.
details about the study here

Recommended use:

One gram of StemEnhance™ triggers an average 25-30% increase in the number of circulating stem cells. The effect lasts for a few hours. The recommended dosage is therefore 2 capsules once or twice a day, at least 6 hours apart.

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See also:

- Stem Cells and StemEnhance by Christian Drapeau, MSc (video)

- Summary of Triple-Blind Study

- Patent Information

- The Story of StemEnhance

Wednesday, February 27, 2008


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Saturday, February 16, 2008

China Stem Cell News

I'm enjoying the news reports from research in China:

Our website is solely dedicated to providing you with up to date and on target information on stem cells, research and current treatments available in China. It is our mission to inform and educate the world via increased communication on the fast breaking and leading edge medical opportunities available to those in need. We are here to bridge the gap between, researchers, scientists, laboratories, doctors, care providers and those seeking treatment; you. It is our goal to create a smooth road and easy travel between patients and the medical care they need. We are Stem Cells China Limited, a company of dedicated individuals offering you the latest facts and information about stem cells and their use in China.

We also provide a discussion group that provides new updates on treatments and research in China and throughout the world and also allows people interested in treatments to get in touch with those who have already had treatment: China Stem Cells. There are two other non-affiliated groups that we feel are helpful for people interested in stem cell research and treatments in general: Stem Cell Safety and Brain Injury Alternatives for Kids.

If you are interested in getting more information about finding a treatment in China for a specific ailment, and you are in North America, you can call us toll free at 1-877-2STEMCELLS or contact us by e-mail.

Saturday, February 2, 2008

Stem Cell Activity In The Aging Brain

Stem Cell Activity Deciphered In The Aging Brain

ScienceDaily (Dec. 18, 2006) — Neurobiologists have discovered why the aging brain produces progressively fewer new nerve cells in its learning and memory center. The scientists said the finding, made in rodents, refutes current ideas on how long crucial "progenitor" stem cells persist in the aging brain.

The finding also suggests the possibility of treating various neurodegenerative disorders, including Alzheimer's disease, dementia and depression, by stimulating the brain's ability to produce new nerve cells, said senior study investigator Ashok K. Shetty, Ph.D., professor of neurosurgery at Duke University Medical Center and medical research scientist at Durham VA Medical Center.

Results of the study appear online in the journal Neurobiology of Aging. The research was funded by the National Institutes of Health and the U.S. Department of Veterans Affairs.

Previous studies by Shetty and others had demonstrated that as the brain ages, fewer new nerve cells, or neurons, are born in the hippocampus, the brain's learning and memory center. In one study, Shetty and colleagues showed that the production of new neurons in rats slows down dramatically by middle age -- the equivalent of 50 years in humans.

But scientists did not know what causes this decline.

The common assumption had been that the brain drain was due to a decreasing supply of neural stem cells in the aging hippocampus, said lead study investigator Bharathi Hattiangady, Ph.D., research associate in neurosurgery. Neural stem cells are immature cells that have the ability to give rise to all types of nerve cells in the brain.

In the current study, however, the researchers found that the stem cells in aging brains are not reduced in number, but instead they divide less frequently, resulting in dramatic reductions in the addition of new neurons in the hippocampus.

To conduct their census, the researchers attached easy-to-spot fluorescent tags to the neuronal stem cells in the hippocampus in young, middle-aged and old rats.

They found that in young rats, the hippocampus contained 50,000 stem cells -- and, significantly, this number did not diminish with aging. This finding, the researchers said, suggested that the decreased production of new neurons in the aged brain was not due to a lack of starting material.

The researchers then used another fluorescent molecule to tag all stem cells that were undergoing division in the process of staying "fresh" in case they were recruited to become mature nerve cells.

They found that in young rats, approximately 25 percent of the neural stem cells were actively dividing, but only 8 percent of the cells in middle-aged rats and 4 percent in old rats were dividing. This decreased division of stem cells is what causes the decreased neurogenesis, or birth of nerve cells, seen with aging, the scientists said.

"This discovery provides a new avenue to pursue in trying to combat the cognitive decline associated with conditions such as Alzheimer's disease and with aging in general," Hattiangady said.

The team now is searching for ways to stimulate the brain to replace its own cells in order to improve learning and memory function in the elderly.

One approach being explored is to treat older rats with drugs designed to mimic the action of compounds called neurogenic factors, which encourage stem cells in the brain to divide, Shetty said. The researchers also are grafting neural stem cells grown in culture dishes into the hippocampus, to stimulate those already present. Additional approaches include using behavioral modification techniques, such as physical exercise and exposure to an enriching environment, that are known to stimulate proliferation of stem cells.

Adapted from materials provided by Duke University Medical Center.

Duke University Medical Center (2006, December 18). Stem Cell Activity Deciphered In The Aging Brain. ScienceDaily. Retrieved February 2, 2008, from­ /releases/2006/12/061218122558.htm

Stem cells in an aged rat brain. (Image courtesy of Duke University Medical Center)

Control Of Stem Cell Aging

Dual Intrinsic And Extrinsic Control Of Stem Cell Aging Demonstrated

ScienceDaily (Oct. 13, 2007) — The Stowers Institute’s Xie Lab has published recent findings that reveal some of the factors underlying the aging of stem cells.

It is widely postulated that a decrease in the number and activity of stem cells contributes to the aging of human tissue. These changes could be fundamental to many symptoms of aging such as wrinkling of skin and decreased organ function.

The control of stem cell aging has, until now, been poorly understood, but the Xie Lab has demonstrated that specific factors are associated with an age-dependent decline in the function of stem cells and their microenvironment, called a niche.

“In this study, we used Drosophila (fruit fly) ovarian germline stem cells (GSCs) as a model to demonstrate that age-dependent decline in the functions of stem cells and their niche contributes to overall aging of stem cells,” said Mr. Pan. “We examined three factors in the control of stem cell aging and found evidence that it is controlled both extrinsically and intrinsically.”

First, the team examined a family of proteins called bone morphogenic proteins (BMPs), which plays an important role in the development of many tissues. They found that as BMP signaling activity from the niche decreases with age, the stem cell’s ability to proliferate is compromised, and the stem cell population declines. Conversely, they established that an increase in BMP signaling can prolong the lifespan of stem cells and promote proliferation.

Second, the team established that time also takes a toll on the adhesion between stem cells and their niche. Strong adhesion can prolong a stem cell’s lifespan, and weakened adhesion can enhance stem cell aging.

Finally, the paper highlights how over-expression of an enzyme that helps eliminate free oxygen species, either in GSCs or in their niche, can prolong the lifespan of stem cells and increase proliferation.

“Inefficient replacement of worn-out cells in adult tissues due to the declining function of stem cells over time may be a primary cause of human aging,” says Dr. Xie. “If we learn how to slow down stem cell aging by manipulating functions of stem cells and/or their niche, we may be able to slow down human aging and the progression of age-related degenerative diseases.”

The paper, “Stem Cell Aging is Controlled both Intrinsically and Extrinsically in the Drosophila Ovary,” was published in the Oct. 11 issue of Cell Stem Cell. Lei Pan, Predoctoral Researcher, and Ting Xie, Ph.D., Associate Investigator, are the paper’s first and last authors, respectively.

Additional authors from the Stowers Institute include Shuyi Chen, Predoctoral Researcher; Changjiang Weng, Ph.D., Postdoctoral Research Associate; Dongxiao Zhu, Ph.D., Biostatistician; and Nian Zhang, Ph.D., Research Scientist. Hong Tang of the Center for Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, also contributed to the paper.

Adapted from materials provided by Stowers Institute for Medical Research.

Carbohydrate Regulates Stem Cell Potency

ScienceDaily (Feb. 1, 2008) — Heparan sulfate, a carbohydrate molecule that coats certain proteins on the cell surface, is critical for the proper proliferation and potency of embryonic stem cells, researchers report.

Stem cells' tremendous therapeutic potential arises from their ability to continually self-renew and turn into any adult cell type. Researchers have long been trying to uncover the basis of these abilities, but while several proteins and growth factors are known to play a role both inside and outside the cell, the molecular mechanisms remain largely unknown.

Many of the stem-cell associated can attach to heparan sulfate molecules, so Shoko Nishihara and colleagues examined what would happen to mouse stem cells in cell culture if heparan sulfate production was reduced or blocked. They discovered that three of the major external factors promoting stem cell renewal (proteins called Wnt, FGF, and BMP) could not induce the proper signals inside the cell without heparan sulfate (HS).

As a result, HS deficient cells grew more slowly, and also spontaneously differentiated into other cells more often, at rates that correlated with the level of inhibition. Nishihara and colleagues propose that heparan sulfate might be the cell-surface component that mediates the external and internal signals promoting stem cell renewal, and could be an important target for stem cell engineering.

Adapted from materials provided by American Society for Biochemistry and Molecular Biology, via EurekAlert!, a service of AAAS.


American Society for Biochemistry and Molecular Biology (2008, February 1). Carbohydrate Regulates Stem Cell Potency. ScienceDaily. Retrieved February 2, 2008, from­ /releases/2008/02/080201131223.htm

Model displayes external factors that act to block stem cells from differentiating into different types of adult tissue. LIF activates STAT3 and blocks non-neural differentiation by induction of Myc, while BMP/Smad signaling through HS chains blocks neural differentiation by induction of Id. Wnt/b-catenin signaling through HS chains blocks primitive endodermal differentiation by induction of Nanog. FGF may contribute to proliferation through HS chains. HS chain dependent signaling by unknown factors may regulate proliferation and Oct3/4 expression. (Credit: Shoko Nishihara)